Mano Negra was a French/Spanish/Portuguese band fronted by Manu Chao, born in Paris, France to Spanish parents. The band was founded in 1987 by Manu, his brother Antoine, and his cousin Santiago Casiriego. It split circa 1995, but many members had already left in 1992.

The band was formed from the fusion of 2 smallers bands, the Hot Pants and the Casse-pieds.

Mano Negra mixed a number of styles: straight rock (with a lead guitar), latin music (with a brass section), punk (influenced by The Clash).